MTA2 anticorps (C-Term)

N° du produit ABIN453277

Cet anticorps Lapin Polyclonal détecte spécifiquement MTA2 dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour MTA2 anticorps (C-Term) (ABIN453277)

Antigène: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTA2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-MTA2 anticorps

Épitope: C-Term

Specificité: This antibody reacts to MTA2.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogène: KLH conjugated synthetic peptide selected from the C-terminal region of human MTA2

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MTA2

Antigène: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Autre désignation: MTA2

Sujet: MTA2 is a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small family of different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.Synonyms: MTA1-L1, MTA1L1, Metastasis-associated 1-like 1, Metastasis-associated protein MTA2, PID, p53 target protein in deacetylase complex

ID gène: 9219

NCBI Accession: NP_004730

UniProt: O94776

Pathways: Chromatin Binding