SPHK2 anticorps (C-Term)

N° du produit ABIN4620337

Cet anticorps Lapin Polyclonal détecte spécifiquement SPHK2 dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SPHK2 anticorps (C-Term) (ABIN4620337)

Antigène: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPHK2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-SPHK2 anticorps

Épitope: C-Term

Specificité: This antibody reacts to SPHK2.

Purification: Affinity Purified

Immunogène: Synthetic peptide derived from the C-terminal of Sphingosine Kinase 2

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1: 200. ELISA. Positive Control: Active Recombinant Sphingosine Kinase Enzyme.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped on dry ice. Store (in aliquots) at -20 °C only.

Détails sur SPHK2

Antigène: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Autre désignation: Sphingosine Kinase 2 / SPK2

Sujet: Sphingosine Kinase 2 (Sphk2) catalyzes the phosphorylation of sphingosine to sphingosine 1-phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors). These receptors couple to multiple G proteins (e.g. S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide range of cellular events including cell motility, survival, apoptosis, migration and cell-cell interaction. Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells. S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).Synonyms: SK2, SPHK2

ID gène: 56848

NCBI Accession: NP_064511

UniProt: Q9NRA0

Pathways: VEGF Signaling