SMPD3 anticorps

N° du produit ABIN4620370

Détail du produit anti-SMPD3 anticorps

Antigène: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMPD3 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects Sphingomyelin Phosphodiesterase 3, predominantly expressed in the brain.

Purification: Affinity chromatography

Immunogène: Synthetic peptide derived from human sphingomyelin phosphodiesterase 3

Information d'application

Indications d'application: Western blot (1: 400 starting dilution). Protein appears to run lower than expected proteinmolecular weight. However, antibody is specific for the protein and band blocks whenblocking peptide used.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Détails sur SMPD3

Antigène: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Autre désignation: SMPD3 (SMPD3 Produits)

Synonymes: anticorps 4631433G07Rik, anticorps AI427456, anticorps AW537966, anticorps fro, anticorps nSMase2, anticorps cca1, anticorps NSMASE2, anticorps sphingomyelin phosphodiesterase 3, anticorps sphingomyelin phosphodiesterase 3, neutral, anticorps SMPD3, anticorps Smpd3

Sujet: Sphingomyelin phosphodiesterase 3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these two cellular events independently. It also hydrolyzes sphingosylphosphocholine. Sphingomyelin phosphodiesterase 3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It likely acts as a regulator of postnatal development and participates in bone and dentin mineralization. It is activated by unsaturated fatty acids and phosphatidylserine. it is predominantly expressed in the brain.Synonyms: Neutral sphingomyelinase 2, Neutral sphingomyelinase II, Sphingomyelin phosphodiesterase 3

ID gène: 55512

NCBI Accession: NP_061137

UniProt: Q9NY59

Pathways: Hormone Transport