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Integrin Alpha2b anticorps

CD41 Reactivité: Humain FACS, IHC (fro), IF, IP, ICC Hôte: Souris Monoclonal M148 unconjugated

N° du produit ABIN4880137

Fiche de données

Antigène Voir toutes Integrin Alpha2b (CD41) Anticorps

Integrin Alpha2b (CD41)
Reactivité
114

34

21

5

5

4

3

2

2

2

1

1

1

1

1
Humain
Hôte
75

41

25
Souris
Anticorps secondaires appropriés
Clonalité
96

39

1
Monoclonal
Conjugué
55

16

12

11

5

4

4

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp Integrin Alpha2b est non-conjugé
Application
99

45

26

26

21

18

13

13

10

10

8

4

3

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificité

This antibody recognises integrin alpha 2b, a 110-130 kDa transmembrane protein that is also known as CD41. CD41 associates with the integrin CD61 to form the CD41/CD61 (GPIIb/IIIa) heterodimer, a fibronectin receptor expressed in platelets. The antibody M148 binds to some medulloblastoma and neuroblastoma cells and rhabdomyosarcoma and certain other solid tumours. No binding is observed to marrow constituents other than platelets and megakaryocytes. The antibody M148 prevents aggregation of platelets.

Purification

Purified on protein A from tissue culture supernatant.

Immunogène

Homogenized human medulloblastoma tissue.

Clone

M148

Isotype

IgG1

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anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibody
CD41 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated

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CD41 Reactivité: Humain, Non-Human Primate FACS, IHC (fro) Hôte: Souris Monoclonal HIP8 unconjugated

Indications d'application

Optimal antibody dilution should be determined by titration

Commentaires

Myeloma, fusion partners: Cells from immunized Balb/c mice were fused with the P3X63Ag8.653 myeloma cell line

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Purified IgG supplied in Phosphate buffered saline (PBS) containing 0.09 % Sodium azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Antigène

Integrin Alpha2b (CD41)

Autre désignation

CD41 (CD41 Produits)

Synonymes

anticorps AI172977, anticorps CD41, anticorps CD41B, anticorps GpIIb, anticorps alphaIIb, anticorps BDPLT16, anticorps BDPLT2, anticorps GP2B, anticorps GPIIb, anticorps GT, anticorps GTA, anticorps HPA3, anticorps integrin alpha 2b, anticorps integrin subunit alpha 2b, anticorps Itga2b, anticorps ITGA2B

ID gène

3689

OMIM

607759

UniProt

P20701

Pathways

Integrin Complex