C5AR1 anticorps

N° du produit ABIN488049

Cet anticorps anti-C5AR1 Polyclonal Lapin (ABIN488049) détecte spécifiquement C5AR1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour C5AR1 anticorps (ABIN488049)

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C5AR1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-C5AR1 anticorps

Specificité: Recognizes Complement Component 5a Receptor 1/ CD88 (C5AR1)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogène: C5AR1 antibody was raised against synthetic peptide from human C5AR1 / C5AR. .Remarks: Mouse Homology: 0% (Identity) / 0% (Similarity) Rat Homology: 27% (Identity) / 66% (Similarity)

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 10 μg/mLThis antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after proteinase K antigenretrieval. After incubation with the primary antibody, slides were incubated withbiotinylated secondary antibody LS-D1, followed by alkaline phosphatase-streptavidin andchromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Détails sur C5AR1

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Autre désignation: CD88 / C5R1

Sujet: The human anaphylatoxin C5a is a 74 residue glycopeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a can be demonstrated, rendering this molecule an important mediartor of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP binding coupled receptor that belongs to the rhodopsin supergene family. C5a receptor 1 expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. ESTs have been isolated from B cell/lung/testis, nerve, and placenta libraries.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1

ID gène: 728

NCBI Accession: NP_001727

UniProt: P21730

Pathways: Système du Complément