SOCS5 anticorps (N-Term)

N° du produit ABIN488053

Cet anticorps Lapin Polyclonal détecte spécifiquement SOCS5 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SOCS5 anticorps (N-Term) (ABIN488053)

Antigène: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SOCS5 anticorps

Épitope: AA 1-11, N-Term

Specificité: Recognizes Suppressor of Cytokine Signaling 5 (SOCS5).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogène: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 11 of SOCS5.

Information d'application

Indications d'application: Western blotting: 1/500-1/3000. Immunohistochemistry on Paraffin Sections: 1/100-1/500. Positive Controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 1 x PBS, 40 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C.

Détails sur SOCS5

Antigène: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Autre désignation: SOCS5 / CIS6

Sujet: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.Synonyms: CIS-6, CISH5, CISH6, Cytokine-inducible SH2 protein 6, Cytokine-inducible SH2-containing protein 5, KIAA0671, SOCS-5, Suppressor of cytokine signaling 5

ID gène: 9655, 9606

UniProt: O75159

Pathways: Signalistation JAK/STAT, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process