LDHB anticorps (AA 237-334)

N° du produit ABIN4886658

Détail du produit anti-LDHB anticorps

Antigène: LDHB (Lactate Dehydrogenase B (LDHB))

Épitope: AA 237-334

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LDHB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for L-lactate dehydrogenase B chain(LDHB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for L-lactate dehydrogenase B chain(LDHB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: lactate dehydrogenase B
Protein Name: L-lactate dehydrogenase B chain

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human LDHB recombinant protein (Position: E237-L334). Human LDHB shares 98% amino acid (aa) sequence identity with both mouse and rat LDHB.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur LDHB

Antigène: LDHB (Lactate Dehydrogenase B (LDHB))

Autre désignation: LDHB (LDHB Produits)

Synonymes: anticorps LDH-B, anticorps LDH-H, anticorps LDHBD, anticorps TRG-5, anticorps AI790582, anticorps H-Ldh, anticorps Ldh-2, anticorps Ldh2, anticorps ldh-h, anticorps ldh2, anticorps ldhb, anticorps ldhba, anticorps trg-5, anticorps LDHB, anticorps LDH-B-A, anticorps wu:fa16d07, anticorps wu:fa20c10, anticorps wu:fa96a08, anticorps LDH-B-B, anticorps zgc:92882, anticorps lactate dehydrogenase B, anticorps lactate dehydrogenase B S homeolog, anticorps lactate dehydrogenase Ba, anticorps lactate dehydrogenase Bb, anticorps LDHB, anticorps Ldhb, anticorps ldhb.S, anticorps ldhb, anticorps ldhba, anticorps ldhbb

Sujet: The LDHB gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Synonyms: HEL S 281 | LDHB | LDH-B | LDH B | LDHH | LDH-H | LDH H | LDHBD | TRG-5 | TRG5 | P07195

ID gène: 3945

UniProt: P07195

Pathways: L'effet Warburg