RECQL2 anticorps (AA 122-240)
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- Antigène Voir toutes RECQL2 (WRN) Anticorps
- RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
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Épitope
- AA 122-240
- Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RECQL2 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Rabbit IgG polyclonal antibody for Werner syndrome ATP-dependent helicase(WRN) detection. Tested with WB in Human,Rat.
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Werner syndrome ATP-dependent helicase(WRN) detection. Tested with WB in Human,Rat.
Gene Name: Werner syndrome RecQ like helicase
Protein Name: Werner syndrome ATP-dependent helicase - Purification
- Immunogen affinity purified.
- Immunogène
- E. coli-derived human WRN recombinant protein (Position: Q122-N240). Human WRN shares 84% amino acid (aa) sequence identity with mouse WRN.
- Isotype
- IgG
- Top Product
- Discover our top product WRN Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Antigène
- RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
- Autre désignation
- WRN (WRN Produits)
- Synonymes
- anticorps RECQ3, anticorps RECQL2, anticorps RECQL3, anticorps xBLM, anticorps recq2, anticorps recql2, anticorps recql3, anticorps AI846146, anticorps ffa-1, anticorps xwrn, anticorps RGD1564788, anticorps Werner syndrome RecQ like helicase, anticorps mediator of RNA polymerase II transcription subunit 34, anticorps Bloom syndrome RecQ like helicase, anticorps Werner syndrome, RecQ helicase-like L homeolog, anticorps WRN, anticorps LOC9327212, anticorps blm, anticorps Wrn, anticorps wrn.L
- Sujet
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Werner syndrome ATP-dependent helicase, also known as DNA helicase, RecQ-like type 3, is an enzyme that in humans is encoded by the WRN gene. This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.
Synonyms: Exonuclease WRN | RecQ3 | RECQL2 | RECQL3 | WRN | Q14191 - ID gène
- 7486
- UniProt
- Q14191
- Pathways
- Réparation de l'ADN
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