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Cytochrome C anticorps (AA 1-69)

Cet anticorps Lapin Polyclonal détecte spécifiquement Cytochrome C dans WB et ELISA. Il présente une réactivité envers Humain, Rat et Souris.
N° du produit ABIN4901338

Aperçu rapide pour Cytochrome C anticorps (AA 1-69) (ABIN4901338)

Antigène

Voir toutes Cytochrome C (CYCS) Anticorps
Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Reactivité

  • 199
  • 164
  • 137
  • 59
  • 53
  • 53
  • 49
  • 47
  • 41
  • 19
  • 6
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Rat, Souris

Hôte

  • 117
  • 98
  • 5
  • 1
Lapin

Clonalité

  • 141
  • 79
  • 1
Polyclonal

Conjugué

  • 110
  • 16
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Cet anticorp Cytochrome C est non-conjugé

Application

  • 171
  • 92
  • 82
  • 64
  • 39
  • 34
  • 31
  • 27
  • 22
  • 19
  • 14
  • 12
  • 11
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Épitope

    • 41
    • 16
    • 9
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-69

    Fonction

    CYCS is a protein encoded by the CYCS gene which is approximately 11,7 kDa. CYCS is localised to the mitochondrion intermembrane space. It is involved in the TNFR1 pathway, respiratory electron transport and apoptosis modulation and signalling. It is a small heme protein that functions as a central component of the electron transport chain in the mitochondria. It associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. It is also involved in the initiation of apoptosis. CYCS is expressed in the nervous system, liver, kidney, heart and muscle. Mutations in the CYCS gene may result in thrombocytopenia. STJ98953 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody detects endogenous CYCS.

    Specificité

    The antibody detects endogenous CYCS.

    Attributs du produit

    Rabbit Polyclonal to CYCS.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    Immunogène

    Synthetic peptide from human CYCS protein.

    Isotype

    IgG
  • Indications d'application

    WB 1:500-2000
    ELISA 1:10000-20000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • Antigène

    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

    Autre désignation

    CYCS

    Poids moléculaire

    15kDa

    ID gène

    54205

    UniProt

    P99999

    Pathways

    Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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