E2F1 anticorps (acLys120)
Aperçu rapide pour E2F1 anticorps (acLys120) (ABIN4901413)
Antigène
Voir toutes E2F1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 100-170, acLys120
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Fonction
- E2F-1 is a protein encoded by the E2F1 gene which is approximately 46,9 kDa. E2F-1 is localised to the nucleus. It is involved in glioma, cyclins and cell cycle regulation and activation of BH3-only proteins. It plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. E2F-1 is expressed in the skin, pancreas and the nervous system. Mutations in the E2F1 gene may result in retinoblastoma pharyngoconjunctival fever. STJ97800 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous levels of E2F-1 (Acetyl Lys120).
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Specificité
- The antibody detects endogenous E2F-1 (Acetyl-Lys120) protein
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Attributs du produit
- Rabbit Polyclonal to E2F-1 (Acetyl-Lys120).
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogène
- Synthetic peptide from AA range: 100-170.
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Isotype
- IgG
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Indications d'application
- WB 1:5000-10000 ELISA 1:10000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- E2F1 (E2F Transcription Factor 1 (E2F1))
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Autre désignation
- E2F-1
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ID gène
- 1869
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UniProt
- Q01094
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Pathways
- Signalisation p53, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
Antigène
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