Neurotrophin 3 anticorps (AA 180-230)

N° du produit ABIN4902031

Détail du produit anti-Neurotrophin 3 anticorps

Antigène: Neurotrophin 3 (NTF3)

Épitope: AA 180-230

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurotrophin 3 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: NT-3 is a protein encoded by the NTF3 gene which is approximately 29,4 kDa. NT-3 is secreted and is involved in apoptotic pathways in synovial fibroblasts, the GPCR pathway, ERK signalling, TGF-beta pathway and nanog in mammalian ESC pluripotency. This protein falls under the neurotrophin family. It controls survival and differentiation of mammalian neurons and is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo. NT-3 is expressed in the brain and peripheral tissues. Mutations in the NTF3 gene result in diabetic neuropathy and pediatric fibrosarcoma. STJ98718 was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This polyclonal antibody binds to endogenous NT-3.

Specificité: The antibody detects endogenous NT-3.

Attributs du produit: Rabbit Polyclonal to NT-3.

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthetic peptide from human NT-3 protein.

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:50-300
ELISA 1:5000-20000

Commentaires:

Brain and peripheral tissues.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS,  pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur Neurotrophin 3

Antigène: Neurotrophin 3 (NTF3)

Autre désignation: NT-3 (NTF3 Produits)

Synonymes: anticorps HDNF, anticorps NGF-2, anticorps NGF2, anticorps NT3, anticorps NT-3, anticorps wu:fl98d04, anticorps hdnf, anticorps ngf-2, anticorps ngf2, anticorps nt-3, anticorps nt3, anticorps NTF3, anticorps AI316846, anticorps AI835689, anticorps Nt3, anticorps Ntf-3, anticorps neurotrophin 3, anticorps neurotrophin 3 S homeolog, anticorps neurotrophin 3 L homeolog, anticorps NTF3, anticorps ntf3, anticorps ntf3.S, anticorps Ntf3, anticorps ntf3.L

ID gène: 4908

UniProt: P20783

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway