IL12RB2 anticorps

N° du produit ABIN4904030

L’anticorps Lapin Polyclonal anti-IL12RB2 a été validé pour WB. Il convient pour détecter IL12RB2 dans des échantillons de Souris et Rat.

Aperçu rapide pour IL12RB2 anticorps (ABIN4904030)

Antigène: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12RB2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL12RB2 anticorps

Attributs du produit: The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.

Purification: Affinity purification

Immunogène: Recombinant protein of human IL12RB2.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C.

Détails sur IL12RB2

Antigène: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Autre désignation: IL12RB2

ID gène: 3595

UniProt: Q99665

Pathways: Signalistation JAK/STAT