Cortactin anticorps
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- Antigène Voir toutes Cortactin (CTTN) Anticorps
- Cortactin (CTTN)
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Cortactin est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain
- Purification
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
- Immunogène
- Purified His-tagged Cortactin protein(Fragment) was used to produced this monoclonal antibody.
- Clone
- 1T3
- Isotype
- IgM
- Top Product
- Discover our top product CTTN Anticorps primaire
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- Indications d'application
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- Cortactin (CTTN)
- Autre désignation
- Cortactin (CTTN Produits)
- Synonymes
- anticorps EMS1, anticorps 1110020L01Rik, anticorps Ems1, anticorps Cttnb, anticorps CG3637, anticorps Dmel\CG3637, anticorps cortactin, anticorps cttn, anticorps CTTN1, anticorps P85.25, anticorps Cttn, anticorps ems1, anticorps CTTN, anticorps cortactin, anticorps CG3637 gene product from transcript CG3637-RD, anticorps cortactin S homeolog, anticorps cortactin L homeolog, anticorps src substrate cortactin, anticorps Src substrate cortactin, anticorps CTTN, anticorps Cttn, anticorps Cortactin, anticorps cttn.S, anticorps cttn.L, anticorps cttn, anticorps CpipJ_CPIJ006351, anticorps Bm1_57220, anticorps LOC100533277
- Sujet
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Synonyms: EMS1, Src substrate cortactin, Amplaxin, Oncogene EMS1, CTTN
Background: Contributes to the organization of the actin cytoskeleton and cell shape (PubMed:21296879). Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density (By similarity). Plays a role in the invasiveness of cancer cells, and the formation of metastases (PubMed:16636290). Plays a role in focal adhesion assembly and turnover (By similarity). In complex with ABL1 and MYLK regulates cortical actin-based cytoskeletal rearrangement critical to sphingosine 1-phosphate (S1P)-mediated endothelial cell (EC) barrier enhancement (PubMed:20861316). Plays a role in intracellular protein transport and endocytosis, and in modulating the levels of potassium channels present at the cell membrane (PubMed:17959782). Plays a role in receptor-mediated endocytosis via clathrin-coated pits (By similarity). Required for stabilization of KCNH1 channels at the cell membrane (PubMed:23144454).
- ID gène
- 2017
- UniProt
- Q14247
- Pathways
- Signalisation MAPK
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