CXCR4 anticorps (AA 151-300)

N° du produit ABIN4908443

L’anticorps Lapin Polyclonal anti-CXCR4 a été validé pour WB, ELISA et FACS. Il convient pour détecter CXCR4 dans des échantillons de Souris et Rat.

Aperçu rapide pour CXCR4 anticorps (AA 151-300) (ABIN4908443)

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR4 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-CXCR4 anticorps

Épitope: AA 151-300

Réactivité croisée: Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse CXCR4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CXCR4

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Autre désignation: CXCR4

Sujet:

Synonyms: CD184, LESTR, Sdf1r, Cmkar4, PB-CKR, b2b220Clo, PBSF/SDF-1, C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Fusin, Leukocyte-derived seven transmembrane domain receptor, Pre-B-cell-derived chemokine receptor, Stromal cell-derived factor 1 receptor, SDF-1 receptor, Cxcr4

Background: Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity). Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

ID gène: 12767

UniProt: P70658

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events