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FGF6 anticorps

Cet anticorps anti-FGF6 est un anticorps Chèvre Polyclonal détectant FGF6 dans WB, ELISA, Neut et Func. Adapté pour Humain.
N° du produit ABIN490848

Aperçu rapide pour FGF6 anticorps (ABIN490848)

Antigène

Voir toutes FGF6 Anticorps
FGF6 (Fibroblast Growth Factor 6 (FGF6))

Reactivité

  • 41
  • 8
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 40
  • 6
  • 1
  • 1
Chèvre

Clonalité

  • 42
  • 6
Polyclonal

Conjugué

  • 22
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp FGF6 est non-conjugé

Application

  • 41
  • 16
  • 13
  • 13
  • 11
  • 11
  • 11
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Neutralization (Neut), Functional Studies (Func)
  • Specificité

    Recognizes human, recombinant Fibroblast Growth Factor 6 (FGF6). ~50 % cross-reactivity with rhFGF4, less than 5 % cross-reactivity with rhFGF9 and less than 2 % cross-reactivity with FGF-acidic, rhFGF5 and rhFGF7. In direct ELISA, this antibody shows no cross-reactivity with other cytokines tested.

    Purification

    Immunoaffinity purified

    Immunogène

    Human, recombinant Fibroblast Growth Factor 6 (FGF6) from E. coli.

    Type of Immunogen: Recombinant protein

    Isotype

    IgG
  • Indications d'application

    Approved: ELISA (0.5 - 1 μg/mL), Func, Neut, WB (0.1 - 0.2 μg/mL)

    Usage: Suitable for use in Neutralization, Western Blot and ELISA. Neutralization: ND50 is ~0.025-0.075 μg/mL in the presence of 1 ng/mL of rhFGF6 and 1 μg/mL of heparin, using the FGF6 responsive NR6R-3T3 fibroblasts as target cells. The Neutralization Dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. Western Blot: 0.1-0.2 μg/mL with the appropriate secondary reagents to detect human FGF6. The detection limit for rhFGF6 is approximately 2 ng/lane under non-reducing and reducing conditions. ELISA: 0.5-1 μg/mL with the appropriate secondary reagents to detect human FGF6. The detection limit for rhFGF6 is ~0.16 ng/well.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.2, 40 % glycerol.

    Conseil sur la manipulation

    Avoid repeat freeze-thaw cycles.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Antigène

    FGF6 (Fibroblast Growth Factor 6 (FGF6))

    Autre désignation

    FGF6

    Sujet

    Name/Gene ID: FGF6
    Family: HBGF

    Synonyms: FGF6, FGF-6, Fibroblast growth factor 6, HSTF-2, HBGF-6, HST-2, HST2, HSTF2

    ID gène

    2251

    UniProt

    P10767

    Pathways

    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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