FGF6 anticorps

N° du produit ABIN490848

Détail du produit anti-FGF6 anticorps

Antigène: FGF6 (Fibroblast Growth Factor 6 (FGF6))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF6 est non-conjugé

Application: Western Blotting (WB), ELISA, Neutralization (Neut), Functional Studies (Func)

Specificité: Recognizes human, recombinant Fibroblast Growth Factor 6 (FGF6). ~50 % cross-reactivity with rhFGF4, less than 5 % cross-reactivity with rhFGF9 and less than 2 % cross-reactivity with FGF-acidic, rhFGF5 and rhFGF7. In direct ELISA, this antibody shows no cross-reactivity with other cytokines tested.

Purification: Immunoaffinity purified

Immunogène: Human, recombinant Fibroblast Growth Factor 6 (FGF6) from E. coli.

Type of Immunogen: Recombinant protein

Isotype: IgG

Information d'application

Indications d'application: Approved: ELISA (0.5 - 1 μg/mL), Func, Neut, WB (0.1 - 0.2 μg/mL)

Usage: Suitable for use in Neutralization, Western Blot and ELISA. Neutralization: ND50 is ~0.025-0.075 μg/mL in the presence of 1 ng/mL of rhFGF6 and 1 μg/mL of heparin, using the FGF6 responsive NR6R-3T3 fibroblasts as target cells. The Neutralization Dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. Western Blot: 0.1-0.2 μg/mL with the appropriate secondary reagents to detect human FGF6. The detection limit for rhFGF6 is approximately 2 ng/lane under non-reducing and reducing conditions. ELISA: 0.5-1 μg/mL with the appropriate secondary reagents to detect human FGF6. The detection limit for rhFGF6 is ~0.16 ng/well.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 40 % glycerol.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur FGF6

Antigène: FGF6 (Fibroblast Growth Factor 6 (FGF6))

Autre désignation: FGF6 (FGF6 Produits)

Synonymes: anticorps FGF6, anticorps hst2, anticorps fgf-6, anticorps hbgf-6, anticorps HBGF-6, anticorps HST2, anticorps Fgf-6, anticorps HSTF-2, anticorps fgf4, anticorps fgf6, anticorps fibroblast growth factor 6, anticorps fibroblast growth factor 6a, anticorps FGF6, anticorps fgf6, anticorps Fgf6, anticorps fgf6a

Sujet: Name/Gene ID: FGF6
Family: HBGF

Synonyms: FGF6, FGF-6, Fibroblast growth factor 6, HSTF-2, HBGF-6, HST-2, HST2, HSTF2

ID gène: 2251

UniProt: P10767

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway