ITGA6 anticorps

N° du produit ABIN4911222

Cet anticorps anti-ITGA6 est un anticorps Souris Monoclonal détectant ITGA6 dans WB, FACS, IF et IHC (p). Adapté pour Humain.

Aperçu rapide pour ITGA6 anticorps (ABIN4911222)

Antigène: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA6 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 9C5

Détail du produit anti-ITGA6 anticorps

Réactivité croisée: Humain

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: ITA6 recombinant protein is used to produce this monoclonal antibody.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ITGA6

Antigène: ITGA6 (Integrin, alpha 6 (ITGA6))

Autre désignation: ITA6

Sujet:

Synonyms: CD49f, VLA-6, ITGA6B, Integrin alpha-6, CD49 antigen-like family member F, ITGA6

Background: Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).

ID gène: 3655

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex