RYK anticorps

N° du produit ABIN4913824

Cet anticorps Souris Monoclonal détecte spécifiquement RYK dans WB et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour RYK anticorps (ABIN4913824)

Antigène: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RYK est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 1C1

Détail du produit anti-RYK anticorps

Réactivité croisée: Humain

Purification: Purified by Protein G.

Immunogène: This RYK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 260-565 amino acids from human RYK.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur RYK

Antigène: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Autre désignation: RYK

Sujet:

Synonyms: JTK5, RYK1, JTK5A, D3S3195, Tyrosine-protein kinase RYK, RYK

Background: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

ID gène: 6259

UniProt: P34925

Pathways: Signalisation RTK, Signalisation WNT, Regulation of Cell Size