Complement Factor H anticorps
Aperçu rapide pour Complement Factor H anticorps (ABIN492503)
Antigène
Voir toutes Complement Factor H (CFH) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Clone OX-24 inhibits the binding of factor H to surface bound C3. This antibody recognizes the Human serum complement protein factor H and a 43-49 kDa truncated form of factor H.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Attributs du produit
- Synonyms: CFH, HF, HF1, HF2, H factor 1
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Purification
- Protein G Chromatography.
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Immunogène
- Purified Human complement factor H protein
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Isotype
- IgG1
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Indications d'application
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ELISA. Western blot. Immunoprecipitation. Flow Cytometry. Immunohistochemistry on Paraffin Sections: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- Complement Factor H (CFH)
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Sujet
- Factor H (CFH) is a protein with twenty short consensus repeat (SCR) domains. Factor H is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in Factor H have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: CFH, H factor 1, HF, HF1, HF2
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ID gène
- 3075
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UniProt
- P08603
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Pathways
- Système du Complément, Cellular Response to Molecule of Bacterial Origin
Antigène
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