XBP1 anticorps (AA 2-160)
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- Antigène Voir toutes XBP1 Anticorps
- XBP1 (X-Box Binding Protein 1 (XBP1))
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Épitope
- AA 2-160
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Reactivité
- Humain, Souris, Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp XBP1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- Recognizes XBP1/TREB5 (2-160).
- Attributs du produit
- Synonyms: XBP-1, XBP2, X-box-binding protein 1, Tax-responsive element-binding protein 5
- Purification
- Immunoaffinity Chromotography.
- Immunogène
- XBP-1 antibody was raised against recombinant protein corresponding to amino acids 2 to160 of Human XBP-1 (Genbank accession No. BAB82982).
- Clone
- 9B7E5
- Isotype
- IgG
- Top Product
- Discover our top product XBP1 Anticorps primaire
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- Indications d'application
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ELISA. Western Blot: XBP1 antibody can be used for detection of XBP1 at 0.5-1 μg/mL. Positive Control: XBP-1 Recombinant Protein. Immunocytochemistry: 2 μg/mL. Positive Control: HepG2 cells. Immunohistochemistry on Paraffin Sections: 10 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
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Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch. - Date de péremption
- 12 months
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- Antigène
- XBP1 (X-Box Binding Protein 1 (XBP1))
- Autre désignation
- XBP1 / TREB5 (XBP1 Produits)
- Synonymes
- anticorps treb5, anticorps xXBP1, anticorps xbp2, anticorps XBP1P1, anticorps XBPP1, anticorps xbp1, anticorps TREB5, anticorps XBP-1, anticorps XBP2, anticorps D11Ertd39e, anticorps TREB-5, anticorps HTF, anticorps cb918, anticorps id:ibd1195, anticorps trebf, anticorps wu:fb02h05, anticorps wu:fb63f10, anticorps xbp1a, anticorps xbp1b, anticorps X-box binding protein 1, anticorps X-box binding protein 1 L homeolog, anticorps xbp1, anticorps XBP1, anticorps Xbp1, anticorps xbp1.L
- Sujet
- X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER) (1). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94 (3,4).Synonyms: Tax-responsive element-binding protein 5, X-box-binding protein 1, XBP-1, XBP2
- ID gène
- 7494
- UniProt
- P17861
- Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
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