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Cadherin-16 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement Cadherin-16 dans IF, FACS et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN4949253

Aperçu rapide pour Cadherin-16 anticorps (ABIN4949253)

Antigène

Voir toutes Cadherin-16 (CDH16) Anticorps
Cadherin-16 (CDH16)

Reactivité

  • 111
  • 50
  • 40
  • 24
  • 23
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 60
  • 53
  • 1
Lapin

Clonalité

  • 68
  • 46
Polyclonal

Conjugué

  • 54
  • 8
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Cadherin-16 est non-conjugé

Application

  • 68
  • 50
  • 39
  • 38
  • 29
  • 20
  • 18
  • 11
  • 5
  • 4
  • 3
  • 1
Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Purification

    Protein A affinity chromatography

    Immunogène

    A recombinant human protein was used as the immunogen for the Cadherin 16 antibody.

    Isotype

    IgG
  • Indications d'application

    Optimal dilution of the Cadherin 16 antibody to be determined by the researcher.\. FACS: 0.5-1 μg/10e6 cells,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Agent conservateur

    Azide free

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store the Cadherin 16 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène

    Cadherin-16 (CDH16)

    Autre désignation

    Cadherin 16

    Sujet

    Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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