Recombinant S100B anticorps (full length)
Aperçu rapide pour Recombinant S100B anticorps (full length) (ABIN4949395)
Antigène
Voir toutes S100B AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- Recombinant S100B Antibody / Rabbit Monoclonal (azide and preservative free)
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Purification
- Protein A affinity chromatography
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Immunogène
- Full length human recombinant S100B protein was used as the immunogen for this recombinant S100B antibody.
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Isotype
- IgG, kappa
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Indications d'application
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The optimal dilution of the recombinant S100B antibody for each application should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the recombinant S100B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- S100B (S100 Calcium Binding Protein B (S100B))
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Autre désignation
- S100B
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Sujet
- S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
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UniProt
- P04271
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Pathways
- Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
Antigène
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