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CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) anticorps

Cet anticorps anti- est un anticorps Souris Monoclonal détectant dans IHC (p) et IF. Adapté pour Humain.
N° du produit ABIN4949564

Aperçu rapide pour CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) anticorps (ABIN4949564)

Antigène

CFTR / Cystic Fibrosis Transmembrane Regulator

Reactivité

  • 9
  • 4
Humain

Hôte

  • 5
  • 4
Souris

Clonalité

  • 9
Monoclonal

Conjugué

  • 9
Inconjugué

Application

  • 9
  • 7
  • 4
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone

CFTR-1643
  • Épitope

    AA 258-385

    Purification

    Protein G affinity chromatography

    Immunogène

    A partial recombinant protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this CFTR antibody.

    Isotype

    IgG2b
  • Indications d'application

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.\. IF: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Agent conservateur

    Azide free

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène

    CFTR / Cystic Fibrosis Transmembrane Regulator

    Sujet

    Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]

    ID gène

    1080
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