Recombinant CFTR / Cystic Fibrosis Transmembrane Regulator anticorps

N° du produit ABIN5707642

Cet anticorps anti-CFTR / Cystic Fibrosis Transmembrane Regulator Monoclonal Lapin (Clone CFTR-2290R) (ABIN5707642) détecte spécifiquement CFTR / Cystic Fibrosis Transmembrane Regulator dans IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant CFTR / Cystic Fibrosis Transmembrane Regulator anticorps (ABIN5707642)

Antigène: CFTR / Cystic Fibrosis Transmembrane Regulator

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CFTR-2290R

Détail du produit

Fonction: Recombinant CFTR Antibody / Rabbit Monoclonal (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogène: A recombinant human partial protein was used as the immunogen for this recombinant CFTR antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant CFTR antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant CFTR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détail du antigène

Antigène: CFTR / Cystic Fibrosis Transmembrane Regulator

Sujet: Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene. The CFTR gene codes for an ABC transporter-class ion channel protein that conducts chloride and thiocyanate ions across epithelial cell membranes. Mutations of the CFTR gene affecting chloride ion channel function lead to dysregulation of epithelial fluid transport in the lung, pancreas and other organs, resulting in cystic fibrosis. Complications include thickened mucus in the lungs with frequent respiratory infections, and pancreatic insufficiency giving rise to malnutrition and diabetes. These conditions lead to chronic disability and reduced life expectancy. In male patients, the progressive obstruction and destruction of the developing vas deferens (spermatic cord) and epididymis appear to result from abnormal intraluminal secretions, causing congenital absence of the vas deferens and male infertility. [Wiki]

UniProt: P13569