CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) anticorps
Aperçu rapide pour CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) anticorps (ABIN4949564)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- AA 258-385
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Fonction
- CFTR Antibody (azide and preservative free)
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Purification
- Protein G affinity chromatography
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Immunogène
- A partial recombinant protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this CFTR antibody.
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Isotype
- IgG2b, kappa
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Indications d'application
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the CFTR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CFTR / Cystic Fibrosis Transmembrane Regulator
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Sujet
- Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]
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UniProt
- P13569
Antigène
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