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MEFV anticorps

L’anticorps Lapin Polyclonal anti-MEFV a été validé pour WB. Il convient pour détecter MEFV dans des échantillons de Humain, Souris et Rat.
N° du produit ABIN4951702

Aperçu rapide pour MEFV anticorps (ABIN4951702)

Antigène

Voir toutes MEFV Anticorps
MEFV (Mediterranean Fever (MEFV))

Reactivité

  • 23
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 20
  • 2
  • 1
Lapin

Clonalité

  • 22
  • 1
Polyclonal

Conjugué

  • 15
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp MEFV est non-conjugé

Application

  • 18
  • 16
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Purification

    Antigen affinity

    Immunogène

    Amino acids PSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSR of human MEFV were used as the immunogen for the MEFV antibody.

    Isotype

    IgG
  • Indications d'application

    Optimal dilution of the MEFV antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

    Restrictions

    For Research Use only
  • Buffer

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    Stock

    -20 °C

    Stockage commentaire

    After reconstitution, the MEFV antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène

    MEFV (Mediterranean Fever (MEFV))

    Autre désignation

    MEFV / Mediterranean fever

    Sujet

    MEFV (Mediterranean fever) is a human gene that provides instructions for making a protein called pyrin (also known as marenostrin). Pyrin is produced in certain white blood cells (neutrophils, eosinophils and monocytes) that play a role in inflammation and in fighting infection. Inside these white blood cells, pyrin is found with thecytoskeleton, the structural framework that helps to define the shape, size, and movement of a cell. Pyrin's protein structure also allows it to interact with other molecules involved in fighting infection and in the inflammatory response. Although pyrin's function is not fully understood, it likely assists in keeping the inflammation process under control. Research indicates that pyrin helps regulate inflammation by interacting with the cytoskeleton. And Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed.

    UniProt

    O15553

    Pathways

    Positive Regulation of Endopeptidase Activity
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