EIF4E anticorps
Aperçu rapide pour EIF4E anticorps (ABIN4953242)
Antigène
Voir toutes EIF4E AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Protein G affinity
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Immunogène
- A human recombinant protein was used as the immunogen for this EIF4E antibody.
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Isotype
- IgG1
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the EIF4E antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Buffer
- Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
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Stock
- -20 °C
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Stockage commentaire
- Store the EIF4E antibody at -20°C.
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- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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Autre désignation
- EIF4E
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Sujet
- Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. [UniProt]
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UniProt
- P06730
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Pathways
- BCR Signaling
Antigène
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