FADD anticorps

N° du produit ABIN4953248

Cet anticorps anti-FADD Monoclonal Souris (Clone 5A3-C7-G9) (ABIN4953248) détecte spécifiquement FADD dans WB et IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FADD anticorps (ABIN4953248)

Antigène: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FADD est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 5A3-C7-G9

Détail du produit anti-FADD anticorps

Fonction: FADD Antibody

Purification: Protein G affinity

Immunogène: A human recombinant protein was used as the immunogen for this FADD antibody.

Isotype: IgG2a

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the FADD antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS with 50 % glycerol and 0.03 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the FADD antibody at -20oC.

Détails sur FADD

Antigène: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Autre désignation: FADD

Sujet: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. [UniProt]

UniProt: Q13158

Pathways: Apoptose, Signalisation TLR, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades