NLRP12 anticorps

N° du produit ABIN3032018

L’anticorps Souris Monoclonal anti-NLRP12 a été validé pour WB et ELISA. Il convient pour détecter NLRP12 dans des échantillons de Souris.

Aperçu rapide pour NLRP12 anticorps (ABIN3032018)

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NLRP12 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 228CT4-1-3

Détail du produit anti-NLRP12 anticorps

Purification: Purified

Immunogène: This NALP12 antibody was produced from a mouse immunized with NLRP12/NALP12 recombinant protein.

Isotype: IgM kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the NALP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500-1:1500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4°C for up to one month. For long term, aliquot the NALP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur NLRP12

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Autre désignation: NALP12 (NLRP12)

Sujet: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome