ATF6B anticorps (AA 560-589)

N° du produit ABIN3029852

L’anticorps Lapin Polyclonal anti-ATF6B a été validé pour WB, ELISA et IHC. Il convient pour détecter ATF6B dans des échantillons de Humain, Souris et Hamster.

Aperçu rapide pour ATF6B anticorps (AA 560-589) (ABIN3029852)

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Reactivité: Humain, Souris, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF6B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ATF6B anticorps

Épitope: AA 560-589

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 560-589 from the human protein was used as the immunogen for this ATF6 beta antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the ATF6 beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:25,Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ATF6 beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur ATF6B

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Autre désignation: ATF6 beta

Sujet: ATF6 beta is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.

UniProt: Q99941

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction