Aurora A anticorps (AA 93-120)

N° du produit ABIN3030070

Cet anticorps Lapin Polyclonal détecte spécifiquement Aurora A dans WB et ELISA. Il présente une réactivité envers Souris.

Aperçu rapide pour Aurora A anticorps (AA 93-120) (ABIN3030070)

Antigène: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Aurora A anticorps

Épitope: AA 93-120

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 93-120 from the mouse protein was used as the immunogen for this Aurka antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Aurka antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Aurka antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Aurora A

Antigène: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Autre désignation: Aurka

Sujet: Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity (By similarity). Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.

UniProt: P97477

Pathways: Cycle Cellulaire, Asymmetric Protein Localization