Aurora Kinase B anticorps (AA 84-111)

N° du produit ABIN3030074

L’anticorps anti-Aurora Kinase B Polyclonal Lapin est utilisé pour la détection de Aurora Kinase B dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour Aurora Kinase B anticorps (AA 84-111) (ABIN3030074)

Antigène: Aurora Kinase B (AURKB)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora Kinase B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Aurora Kinase B anticorps

Épitope: AA 84-111

Fonction: Aurkb Antibody

Réactivité croisée (Details): Expected species reactivity: Rat

Purification: Antigen affinity

Immunogène: A portion of amino acids 84-111 from the mouse protein was used as the immunogen for this Aurkb antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Aurkb antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Aurkb antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Aurora Kinase B

Antigène: Aurora Kinase B (AURKB)

Autre désignation: Aurkb

Sujet: Aurkb may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity). Phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis. Required for kinetochore localization of BUB1 and SGOL1 (By similarity).

UniProt: O70126

Pathways: TCR Signaling, Cycle Cellulaire, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades