Aurora Kinase C anticorps (AA 1-30)
Aperçu rapide pour Aurora Kinase C anticorps (AA 1-30) (ABIN3030081)
Antigène
Voir toutes Aurora Kinase C (AURKC) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-30
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Fonction
- Aurora-C Antibody
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Purification
- Purified
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Immunogène
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this Aurora-C antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the Aurora-C antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Aurora-C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Aurora Kinase C (AURKC)
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Autre désignation
- Aurora-C
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Sujet
- Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
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UniProt
- Q9UQB9
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Pathways
- Cycle Cellulaire, Maintenance of Protein Location
Antigène
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