BACE2 anticorps (AA 336-365)
Aperçu rapide pour BACE2 anticorps (AA 336-365) (ABIN3030160)
Antigène
Voir toutes BACE2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 336-365
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Purification
- Purified
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Immunogène
- A portion of amino acids 336-365 from the human protein was used as the immunogen for this BACE2 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the BACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the BACE2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
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Autre désignation
- BACE2
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Sujet
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.
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UniProt
- Q9Y5Z0
Antigène
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