Beclin 1 anticorps (AA 181-210)

N° du produit ABIN3030157

Cet anticorps Lapin Polyclonal détecte spécifiquement Beclin 1 dans WB, ELISA et IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Beclin 1 anticorps (AA 181-210) (ABIN3030157)

Antigène: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Beclin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Beclin 1 anticorps

Épitope: AA 181-210

Réactivité croisée (Details): Expected species reactivity: Bovine, Chicken

Purification: Purified

Immunogène: A portion of amino acids 181-210 from the human protein was used as the immunogen for this Beclin 1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Beclin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Beclin 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Beclin 1

Antigène: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Autre désignation: Beclin 1

Sujet: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Beclin 1 plays a role in two fundamentally important cell biological pathways: autophagy and apoptosis. Beclin 1 is thought to function as a VPS and autophagy protein as part of a complex with Class III PI3 kinase, Vps34.

UniProt: Q14457

Pathways: Autophagy