Caspase 10 anticorps (AA 164-192)
Aperçu rapide pour Caspase 10 anticorps (AA 164-192) (ABIN3030290)
Antigène
Voir toutes Caspase 10 (CASP10) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 164-192
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Purification
- Purified
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Immunogène
- A portion of amino acids 164-192 from the human protein was used as the immunogen for this Caspase-10 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the Caspase-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Caspase-10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
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Autre désignation
- Caspase-10
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Sujet
- CASP10 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in the protein are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
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UniProt
- Q92851
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Pathways
- Apoptose, Caspase Cascade in Apoptosis
Antigène
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