CD33 anticorps (AA 88-117)
Aperçu rapide pour CD33 anticorps (AA 88-117) (ABIN3030379)
Antigène
Voir toutes CD33 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 88-117
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 88-117 from the human protein was used as the immunogen for this CD33 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the CD33 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the CD33 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CD33
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Autre désignation
- CD33
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Sujet
- Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). [UniProt]
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UniProt
- P20138
Antigène
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