CD86 anticorps (AA 269-298)

N° du produit ABIN3030429

Cet anticorps anti-CD86 est un anticorps Lapin Polyclonal détectant CD86 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour CD86 anticorps (AA 269-298) (ABIN3030429)

Antigène: CD86

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD86 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CD86 anticorps

Épitope: AA 269-298

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 269-298 from the human protein was used as the immunogen for this CD86 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the CD86 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CD86 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur CD86

Antigène: CD86

Autre désignation: CD86

Sujet: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq].

UniProt: P42081

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation