CDK1 anticorps (AA 1-30)
Aperçu rapide pour CDK1 anticorps (AA 1-30) (ABIN3030602)
Antigène
Voir toutes CDK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-30
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Réactivité croisée (Details)
- Expected species reactivity: Bovine, Chicken, Drosophila, Mouse, Rat, Xenopus
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this CDC2 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the CDC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the CDC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
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Autre désignation
- CDC2
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Sujet
- CDK1/CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
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UniProt
- P06493
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Pathways
- Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
Antigène
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