Connexin 43/GJA1 anticorps (AA 107-138)

N° du produit ABIN3031020

Cet anticorps anti-Connexin 43/GJA1 est un anticorps Lapin Polyclonal détectant Connexin 43/GJA1 dans WB, IHC et ELISA. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour Connexin 43/GJA1 anticorps (AA 107-138) (ABIN3031020)

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Connexin 43/GJA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Connexin 43/GJA1 anticorps

Épitope: AA 107-138

Réactivité croisée (Details): Expected species reactivity: Bovine, Xenopus

Purification: Purified

Immunogène: A portion of amino acids 107-138 from the human protein was used as the immunogen for this Connexin 43 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Connexin 43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Connexin 43 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Connexin 43/GJA1

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Autre désignation: Connexin 43

Sujet: Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.

UniProt: P17302

Pathways: Signalisation MAPK, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization