Cyclin D2 anticorps (AA 1-30)

N° du produit ABIN3030593

L’anticorps Lapin Polyclonal anti-Cyclin D2 a été validé pour WB et ELISA. Il convient pour détecter Cyclin D2 dans des échantillons de Humain.

Aperçu rapide pour Cyclin D2 anticorps (AA 1-30) (ABIN3030593)

Antigène: Cyclin D2 (CCND2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin D2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Cyclin D2 anticorps

Épitope: AA 1-30

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 1-30 from the human protein was used as the immunogen for this Cyclin D2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Cyclin D2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Cyclin D2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Cyclin D2

Antigène: Cyclin D2 (CCND2)

Sujet: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.

UniProt: P30279

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases