DDR2 anticorps (AA 290-320)

N° du produit ABIN3030740

L’anticorps Lapin Polyclonal anti-DDR2 a été validé pour WB et ELISA. Il convient pour détecter DDR2 dans des échantillons de Humain.

Aperçu rapide pour DDR2 anticorps (AA 290-320) (ABIN3030740)

Antigène: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDR2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DDR2 anticorps

Épitope: AA 290-320

Purification: Purified

Immunogène: A portion of amino acids 290-320 from the human protein was used as the immunogen for this DDR2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the DDR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DDR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur DDR2

Antigène: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Autre désignation: DDR2

Sujet: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane and cytoplasmic regions. There are several subclasses of RTKs and TYRO10 belongs to a novel subclass. The deduced amino acid sequence of TYRO10 has a unique extracellular region encompassing a factor VIII-like domain, not previously described for RTKs.

UniProt: Q16832

Pathways: Signalisation RTK