DNMT1 anticorps (AA 881-914)

N° du produit ABIN3030755

L’anticorps anti-DNMT1 Polyclonal Lapin est utilisé pour la détection de DNMT1 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour DNMT1 anticorps (AA 881-914) (ABIN3030755)

Antigène: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNMT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DNMT1 anticorps

Épitope: AA 881-914

Fonction: Dnmt1 Antibody

Purification: Antigen affinity

Immunogène: A portion of amino acids 881-914 from the mouse protein was used as the immungen for the Dnmt1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Dnmt1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Dnmt1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur DNMT1

Antigène: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Autre désignation: Dnmt1

Sujet: Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. Three families of mammalian DNA methyltransferase genes have been identified which include Dnmt1, Dnmt2 and Dnmt3. Dnmt1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality.

UniProt: P13864

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2