E2F1 anticorps (AA 342-371)

N° du produit ABIN3030786

Cet anticorps anti-E2F1 est un anticorps Lapin Polyclonal détectant E2F1 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour E2F1 anticorps (AA 342-371) (ABIN3030786)

Antigène: E2F1 (E2F Transcription Factor 1 (E2F1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp E2F1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-E2F1 anticorps

Épitope: AA 342-371

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 342-371 from the human protein was used as the immunogen for this E2F1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the E2F1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the E2F1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur E2F1

Antigène: E2F1 (E2F Transcription Factor 1 (E2F1))

Autre désignation: E2F1

Sujet: E2F1 is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters. [UniProt]

UniProt: Q01094

Pathways: Signalisation p53, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy