MAPK7 anticorps (AA 527-557)

N° du produit ABIN3031833

Cet anticorps anti-MAPK7 Polyclonal Lapin (ABIN3031833) détecte spécifiquement MAPK7 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour MAPK7 anticorps (AA 527-557) (ABIN3031833)

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-MAPK7 anticorps

Épitope: AA 527-557

Fonction: ERK4 Antibody

Purification: Purified

Immunogène: A portion of amino acids 527-557 from the human protein was used as the immunogen for this ERK4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the ERK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot the ERK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MAPK7

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Autre désignation: ERK4

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.

UniProt: P31152

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling