Estrogen Receptor alpha anticorps (AA 246-273)

N° du produit ABIN3030876

Cet anticorps anti-Estrogen Receptor alpha Monoclonal Souris (Clone 415CT16-3-2-1) (ABIN3030876) détecte spécifiquement Estrogen Receptor alpha dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Estrogen Receptor alpha anticorps (AA 246-273) (ABIN3030876)

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Estrogen Receptor alpha est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 415CT16-3-2-1

Détail du produit anti-Estrogen Receptor alpha anticorps

Épitope: AA 246-273

Fonction: Estrogen Receptor alpha Antibody

Réactivité croisée (Details): Expected species reactivity: Bovine, Mouse, Pig, Rat

Purification: Purified

Immunogène: A portion of amino acids 246-273 from the human protein was used as the immunogen for this Estrogen Receptor alpha antibody.

Isotype: IgG1

Information d'application

Indications d'application: Titration of the Estrogen Receptor alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Estrogen Receptor alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Estrogen Receptor alpha

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Autre désignation: Estrogen Receptor alpha

Sujet: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly