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Glypican 3 anticorps (AA 529-560)

GPC3 Reactivité: Humain, Souris IF, WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3031100
  • Antigène Voir toutes Glypican 3 (GPC3) Anticorps
    Glypican 3 (GPC3)
    Épitope
    • 20
    • 16
    • 13
    • 12
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 529-560
    Reactivité
    • 152
    • 48
    • 47
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 96
    • 55
    • 2
    Lapin
    Clonalité
    • 81
    • 71
    • 1
    Polyclonal
    Conjugué
    • 63
    • 13
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Glypican 3 est non-conjugé
    Application
    • 83
    • 81
    • 70
    • 50
    • 41
    • 26
    • 18
    • 17
    • 6
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Western Blotting (WB), ELISA
    Purification
    Purified
    Immunogène
    A portion of amino acids 529-560 from the human protein was used as the immunogen for this GPC3 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GPC3 Anticorps primaire
  • Indications d'application
    Titration of the GPC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the GPC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    Glypican 3 (GPC3)
    Autre désignation
    GPC3 (GPC3 Produits)
    Synonymes
    anticorps GPC3, anticorps sgb, anticorps dgsx, anticorps sdys, anticorps sgbs, anticorps oci-5, anticorps sgbs1, anticorps DGSX, anticorps GTR2-2, anticorps MXR7, anticorps OCI-5, anticorps SDYS, anticorps SGB, anticorps SGBS, anticorps SGBS1, anticorps Glypican-3, anticorps glypican 3, anticorps gpc3, anticorps GPC3, anticorps Gpc3
    Sujet
    GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
    UniProt
    P51654
    Pathways
    Glycosaminoglycan Metabolic Process
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