Glypican 3 anticorps (AA 465-494)

N° du produit ABIN3031097

L’anticorps Lapin Polyclonal anti-Glypican 3 a été validé pour WB et ELISA. Il convient pour détecter Glypican 3 dans des échantillons de Humain.

Aperçu rapide pour Glypican 3 anticorps (AA 465-494) (ABIN3031097)

Antigène: Glypican 3 (GPC3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glypican 3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Glypican 3 anticorps

Épitope: AA 465-494

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 465-494 from the human protein was used as the immunogen for this GPC3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the GPC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the GPC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Glypican 3

Antigène: Glypican 3 (GPC3)

Autre désignation: GPC3

Sujet: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

UniProt: P51654

Pathways: Glycosaminoglycan Metabolic Process