LDLR anticorps (AA 391-419)

N° du produit ABIN3031637

L’anticorps Lapin Polyclonal anti-LDLR a été validé pour WB, ELISA et FACS. Il convient pour détecter LDLR dans des échantillons de Humain et Souris.

Aperçu rapide pour LDLR anticorps (AA 391-419) (ABIN3031637)

Antigène: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LDLR est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-LDLR anticorps

Épitope: AA 391-419

Réactivité croisée (Details): Expected species reactivity: Rat, Pig, Rabbit, Hamster, Xenopus

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 391-419 from the human protein was used as the immunogen for this LDLR antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the LDLR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the LDLR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur LDLR

Antigène: LDLR (Low Density Lipoprotein Receptor (LDLR))

Autre désignation: LDLR

Sujet: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism