Leptin Receptor anticorps (AA 23-52)

N° du produit ABIN3031603

Détail du produit anti-Leptin Receptor anticorps

Antigène: Leptin Receptor (LEPR)

Épitope: AA 23-52

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Leptin Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: Purified

Immunogène: A portion of amino acids 23-52 from the human protein was used as the immunogen for this Leptin Receptor antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Leptin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Leptin Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Leptin Receptor

Antigène: Leptin Receptor (LEPR)

Autre désignation: Leptin Receptor (LEPR Produits)

Synonymes: anticorps CD295, anticorps LEP-R, anticorps LEPRD, anticorps OB-R, anticorps OBR, anticorps obr, anticorps cd295, anticorps ob-rb, anticorps Fa, anticorps LEPROT, anticorps Leprb, anticorps Modb1, anticorps OB-RGRP, anticorps Obr, anticorps db, anticorps diabetes, anticorps obese-like, anticorps obl, anticorps ObRb, anticorps Ob-R, anticorps Ob-RM, anticorps lepr, anticorps leptin receptor, anticorps leptin receptor S homeolog, anticorps LEPR, anticorps lepr, anticorps Lepr, anticorps lepr.S

Sujet: Leptin, an adipocyte-specific hormone, regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure by acting through the leptin receptor (LEPR). LEPR is a single-transmembrane-domain receptor of the cytokine receptor family that is identical to the mouse diabetes (db) gene product. During weight loss, leptin levels decrease, whereas soluble LEPR levels and the receptor bound fraction of leptin increases. The presence of LEPR in the absorptive cells of the small intestine suggests that leptin may have a physiological role in the regulation of nutrient absorption.

UniProt: P48357

Pathways: Signalistation JAK/STAT, AMPK Signaling, Feeding Behaviour